A COMPREHENSIVE REVIEW OF PHYTOMOLECULES USED IN ANTI-DIABETIC ACTIVITIES
M. Abinaya, R. Kalki, E. Sibichanduru, A. Sivabalan, Sankar Saravanan and S. A. Vadivel*
ABSTRACT
In ancient times various medicinal plants were used for anti-diabetes as well as other disease. In such way, now many medicinal plants are subjected to show the anti-diabetes properties. The medicinal plant shows diabetes potential via activation of NF-kb, favoring pro-inflammatory cytokines, increased expression of inducible nitric oxide synthase, alpha 1 and 1 collagen, anti-oxidant activity and angiogenesis. The present review is about the treatment of anti-diabetes includes the usage of plants and the plant extract. The extracts are taken from the plants and their explants by using different solvents (water, ethanol etc,.) and by using different techniques (infusion, decoction, percolation etc,..) Many studies were conducted to evaluate the extract of plants for anti-diabetes properties. Anti-diabetes process can be classified into two class, they are basic science aspect of anti-diabetes and practical aspect anti-diabetes. The basic science aspect of anti-diabetes deals with the four phases of anti- diabetes and the practical aspect anti-diabetes are subdivided into acute and chronic diabetes. This review validate the traditional claims and development of safe, effective and globally accepted medicinal plants for anti-diabetes. From this, we report various medicinal plant that can be used as anti-diabetic agent around the world.
Keywords: Diabetic, Insulin, Phytomolecules, Antidiabetic.
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