European Journal of Biomedical and Pharmaceutical Sciences

GASTRIC FLOATING DRUG DELIVERY SYSTEMS MATRIX SUSTAINED RELEASE TABLET

Ombabu Goswami*, Dr. Brajesh Kumar Arjariya and Praveen Bhawsar

ABSTRACT

The integration of gastric floating drug delivery systems (GFDDS) with matrix sustained release tablets represents a promising approach to controlled drug delivery, offering extended gastric retention and sustained release kinetics. This study explores the applications, innovations, regulatory considerations, and commercial viability of GFDDS-matrix tablet integration across various therapeutic areas. Key findings highlight the potential benefits in gastrointestinal disorders, chronic diseases, infectious diseases, and neurological disorders. Innovations such as targeted drug delivery, combination therapy, smart drug delivery systems, and nanotechnology hold promise for enhancing therapeutic outcomes. Regulatory considerations, including compliance with pharmacopeial standards, bioequivalence studies, and stability assessments, are crucial for successful commercialization. Implications for the pharmaceutical industry include opportunities for innovation, market expansion, and improved patient care. Future research directions focus on personalized medicine, precision drug delivery, and collaboration between academia, industry, and regulatory agencies. Overall, integrated GFDDS-matrix tablet formulations offer significant potential for advancing drug delivery technologies and improving global health outcomes.

Keywords: Gastric floating drug delivery systems, matrix sustained release tablets, controlled drug delivery, targeted drug delivery, smart drug delivery systems.