Abstract
IN VITRO: ANTIBACTERIAL ACTIVITY OF NELUMBO NUCIFERA (GAERTN.) FLOWER EXTRACTS AGAINST HUMAN PATHOGENS

Manoj Kumar*

ABSTRACT

Antibacterial activity of crude flower extracts of Nelumbo nucifera (Gaertn.) with different solvents (methanol, ethanol and aqueous) was evaluated for antibacterial activity against medically important human pathogenic bacteria, including two gram-positive (Staphylococcus aureus and Streptococcus sp.) as well as two gram-negative (Pseudomonas aeroginosa and Salmonella typhimurium). The different extracts were tested for the presence of antibacterial activity by agar well diffusion assay (AWDA) method. The flower extracts with different solvents showed significant antibacterial activity against all the tested bacterial strains. In the present study, Streptococcus sp. was highly susceptible to the extract as compared with other three bacterial strains. The results also showed that the methanol extract of N. nucifera was the most effective as the widest inhibitory zone was observed as compared to ethanol as well as aqueous extract. The use of flower extracts of the N. nucifera, with known antibacterial properties can be of great significance in therapeutic treatments.

Keywords: Antibacterial activity; Agar well diffusion assay; Nelumbo nucifera; Human pathogens; Solvents.


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