Abstract
POSTERIOR PELVIC EXENTERATION: EVOLUTION FROM PALLIATIVE TO DEFINITIVE MODALITY FOR LOCALLY ADVANCED RECTAL CANCER

*Patel Devang H., Ray Samir and Suthar Pokhraj P.

ABSTRACT

Pelvic exenteration is a supramajor radical surgical procedure first described in 1948 by Brunschwig for locally advanced pelvic neoplasm.[1] Colorectal carcinoma is the fourth most common cancer found in woman and second most common in man.[2, 3] The rectum is the most frequent site involved. More than 50 % of the rectal cancers are presented as locally advanced stage which carry poor prognosis. The procedure was used mostly for palliative intent and carries high morbidity and mortality. But with advent of neoadjuvant treatment protocols and drugs (multidisciplinary treatment), improvement in surgical skills and technologies posterior pelvic exenteration becomes definitive treatment for locally advanced rectal cancer which carries less morbidity and mortality with improvement in oncological outcome.

Keywords: Posterior pelvic exenteration, locally advanced rectal cancer, carcinoembryonic antigen, contrast enhanced computed tomography.


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