Abstract
LATERAL LOCATION OF PLACENTA AND ITS CORRELATION IN PREGNACY INDUCED HYPERTENSION

Dr. Deepti Shrivastava*, Dr. Virul Shrivastava, Dr. Rainee Agarwal and Dr. Chinmaya Khodaskar

ABSTRACT

Patients who develop Pregnancy Induced Hypertension (PIH) have placentation abnormality as the initial event. The musculo-elastic media of the spiral arteries in the myometrium are retained due to the failure of secondary trophoblastic invasion which leads to decreased choriodecidual blood flow and establishment of relative ischemia in the placental bed. This causes an imbalance in the levels of antioxidants and oxidants. Objectives: To find out whether placental laterality, as determined by ultrasound, can be used as a predictor of development of pre-eclampsia. Methodology: Case Control Study for 200 patients was done for 1 year duration from June 2015 to May 2016. All patients attending AVBRH OPD of OBS AND GYN at Sawangi, fitting into the inclusion criteria, with written, informed and valid consent were included in the research. Placental location via ultrasound was studied from 20-24 weeks of gestation and the patients were closely followed up. Patients who developed PIH, were analysed for the association with placental lateralisation. Results: Out of 200 antenatal patients, 100 patients developed preeclampsia in 2nd trimester. Out of these 100 preeclampsia patients, 4(4%) had unilateral location of placenta and 48(48%) had central and 48(48%) had fundal placenta. Conclusion: No significant association between position of placenta and pregnancy induced hypertension could be claimed through our study. Speculations of laterality of placenta being an early predictor of preeclampsia were not to be the case in our set up.

Keywords: placenta, lateralisation, ultrasound, predictor, ischemia, pre-eclampsia.


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