Abstract
“TUMOR ANGIOGENESIS- A REVIEW”

Ramya V., Xavier Pradeep D’mello A.*, T. Vijay Sylvester, Sudeep D’mello A.

ABSTRACT

Angiogenesis is a complex process depending on the coordination of many regulators and thereby activating angiogenic switch. Primary tumor cells, stromal cells and cancer stem cells strongly influence vessel growth. Recent advances in understanding of angiogenic mechanism have lead to the development of several anti-angiogenic and anti-metastatic agents that use the strategy of regulation of angiogenic switch. Targeting angiogenic factors from VEGF (vascular endothelial growth factor) family has become an effective strategy to inhibit tumor growth and so far the most successful results are seen in metastatic squamous cell carcinoma (SCC), renal cell carcinoma (RCC), colorectal cancer (CRC) and non-small cell lung cancer (NSCLC). This review article presents the practicability of several angiogenic parameters and markers that have been employed to conjecture regional metastasis including micro vessel density, positive and negative regulators of angiogenesis and genetic markers for angiogenesis.

Keywords: Angiogenesis, Angiostatin, Endothelial cells, Neovascularisation, Vasculogenesis.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: MAY ISSUE PUBLISHED

    MAY 2022 Issue has been successfully launched on 1 May 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT