European Journal of Biomedical and Pharmaceutical Sciences

PRE TRANSPLANT NEPHRECTOMY, OUR EXPERIENCE IN PRINCE HUSSEIN CENTER OF UROLOGY AND ORGAN TRANSPLANTATION

Ghaith Qsous*, Mohannad Al-Naser, Firas Khori, Mohammad Abd-Aldayem, Rami Gsous, Laith Khasawneh

ABSTRACT

Introduction: The aim of our study is to review our experience in the indications, causes and outcome of pre renal transplant nephrectomy and to compare our data with the international data in the published literatures and to discuss the best timing to perform the native nephrectomy wither to be done prior or during or post transplantation. Methods: This is a prospective study which was carried out in Prince Hussein Center Of Urology and Organ Transplantation in the period from 2010 to 2015. Twenty eight patients underwent pre transplant nephrectomy for various indications. data were collected from the patient file and from direct communication with patient. Results: Out of the 28, patients there were 18 patients had pre - transplant nephrectomy due to polycystic kidney disease (PCKD), six patients had nephrectomy due to recurrent Urinary tract infection (UTI) with renal stones and four patients due to vesicouretral reflux. Two complications were reported out from 28 cases, one patient had splenic injury treated with splenectomy and one patient had bowel injury treated with primary repair. Conclusion: polycystic kidney disease was the most common indication for pre transplant nephrectomy which is the same reported in literature. Also we found that there is decrease in developing of UTI or pyelonehritis after this procedure in patients who had recurrent urinary tract infections. We recommend doing Pre transplant native nephrectomy in patients symptomatic polycystic kidney disease and patients with recurrent infection with renal stones.

Keywords: Kidney Transplant, Nephrectomy, PCKD.