Abstract
MOLECULAR MODELING OF DENDRIMER LIGANDS OF COPPER AND COBALT METAL COMPLEX

Peer Irfan Rashid* and Ab. Rashid Wani

ABSTRACT

The high level of control possible over the architectural design of dendrimers; their size, shape, branching length/density, and their surface functionality, clearly distinguishes these structures as unique and optimum carriers in that application. The bioactive agents may be encapsulated into the interior of the dendrimers or chemically attached/physically adsorbed onto the dendrimer surface, with the option of tailoring the carrier to the specific needs of the active material and its therapeutic applications. In this regard, the high density of exo-presented surface groups allows attachment of targeting groups or functionality that may modify the solution behavior or toxicity of dendrimers.

Keywords: Size, Dendrimers, Therapeutic, Toxicity, Tailoring.


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