Abstract
A COMPARATIVE STUDY ON SAFETY, EFFICACY & COST EFFECTIVENESS OF FERRIC CARBOXYMALTOSE & IRON SUCROSE IN DIALYSIS PATIENTS AT A TERTIARY CARE HOSPITAL

Ansu Anna Dan*, Merlin K. Jacob, Sneha Prabha, Apollo James and T. Sivakumar

ABSTRACT

The objective of our study was to evaluate the safety, efficacy and cost effectiveness of FCM, compared to IV iron sucrose in dialysis patients who have iron deficiency anemia. A prospective observational comparative study was carried out in 69 hemodialysis patients during the period of 6 months in a tertiary care hospital in Southern India. Our results showed that Ferric Carboxymaltose (FCM) was more efficacious, safer and cost effective compared to iron sucrose. Our study highlights on primary efficacy parameters- Hemoglobin(Hb), ferritin, serum iron and transferrin saturation (TSAT). In case of Hb, TSAT, serum iron FCM showed a mean increase 5.267g/dL, 3.2%, 20. 02 μg/dL while iron sucrose showed only 3.30 g/dL, 1.781%, 16.4% μg/dL respectively. While comparing the mean value of serum ferritin levels, FCM showed a decreased level of 69.25% ng/mL decrease whereas for iron sucrose only 53.81 ng/mL was observed. At least one drug-related treatment-emergent ADR occurred in 7 of 40 (17.3%) subjects in the FCM group and 13 of 29 (44.8%) subjects in the iron sucrose group. FCM should be cost effective for the patient and maximal time efficiency for the doctors and healthcare professionals than the iron sucrose. FCM has the advantage of allowing more iron to be administered in fewer infusions in patients with chronic kidney disease. FCM was superior to iron sucrose in replenishing the iron stores.

Keywords: Ferric Carboxymaltose, Hemodialysis, Iron sucrose.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Dr. Dhrubo Jyoti Sen

Download Article : Click here

News & Updation

  • EJBPS: MAY ISSUE PUBLISHED

    MAY 2022 Issue has been successfully launched on 1 May 2022.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT