Abstract
ASSESSMENT OF PREVALENCE AND COMPLICATIONS OF TYPE-II DIABETES MELLITUS

Jaladi Himaja, Nancy Grace Daniel*, Linta Kurian and Battu Rakesh

ABSTRACT

Background: Diabetes mellitus (DM) is an endocrinological and/or metabolic disorder with an accumulative global occurrence and incidence. Diabetes mellitus is a metabolic-cum-vascular syndrome of diverse etiologies characterised by prolonged hyperglycaemia with resultant disturbances of carbohydrate, fat and protein metabolism with subsequent defects in insulin secretion, insulin action or both. Recent guidelines for treating patients with type 2 diabetes mellitus are based on glycaemic standards derived from medical specialty data; nonetheless, the course of the disease, from prediabetes to end-stage complications, is not the similar in all patients. Microvascular complications, comprising nephropathy, retinopathy and neuropathy, are intensely related to haemoglobin A1c (HbA1c). However, vascular complications may headway in patients who have HbA1c <7.0% and may appear even in undiagnosed patients owing to transitory increases in plasma glucose concentrations. Concomitant atherosclerosis and occult macro vascular disease may follow a hastened course in type 2 diabetes. Managing hyperglycaemia in the advanced stages of type 2 diabetes does not appear to be associated with value-added cardiovascular outcomes. The glucotoxicity and lipotoxicity that may precede sustained hyperglycaemia and β-cell dysfunction are initial, reversible pathophysiologic events. This suggests that quick management may modify the course of hyperglycaemia and avert or delay long-term complications. The challenge remains to identify patients with early type 2 diabetes who are at risk for hasty progression of β-cell failure and early development of microvascular complications. Objective: To assess the prevalence and complications of type-II diabetes mellitus. Study Design: A prospective observational study was carried out in the General Medicine Department, Mandya Institute of Medical Sciences and Teaching Hospital, Mandya, Karnataka, using a well-designed patient data collection form. Results: Out of 121 diabetic patients studied 56.20% were males, 43.80% were females. Most of the patients with diabetes fall in the age group of 61-70 years. Among the complications developed macrovascular complications (59%) were having more prevalence rate than microvascular complications (22%). Conclusion: Prevalence of DM was more in males than in females and macro vascular complications were having more prevalence rate than micro vascular complications.

Keywords: Cardiovascular diseases, Multimorbidity, Cardiovascular Events and sedentary lifestyle.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tanima Debnath Sarkar

Download Article : Click here

News & Updation

  • EJBPS: OCTOBER ISSUE PUBLISHED

    OCTOBER 2021 Issue has been successfully launched on 1 October 2021

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT