Abstract
ASSESSMENT OF FREQUENCY, RISK FACTORS, SEVERITY AND PATTERN OF MEDICATION OF PRE-ECLAMPSIA

Vijay Kumar Panthi, Sumit Kumar Karn*, Tekendra Mishra and Nawaraj Basnet

ABSTRACT

Pre-eclampsia is pregnancy-induced hypertension (PIH) of unknown etiology which can be quite serious as it can lead to various complications both for the mother and the baby where as eclampsia is the occurrence of convulsions, not caused by any coincidental neurological disease such as epilepsy. The aim of this study is to assess the frequency, the risk factors, severity and pattern of medication of pre-eclampsia and eclampsia. A prospective, descriptive, cross-sectional, qualitative and quantitative study was conducted among 43 pregnant ladies admitted in the gynae ward of BPKIHS, Dharan, Nepal diagnosed as pre-eclampsia and eclampsia. Direct personal interviews were taken using semi-structured questionnaires consisting of open and closed ends and other data were collected from the register file. Out of 43 patients, 76.74%, 11.63% and 11.63% were suffering from mild pre-eclampsia, severe pre-eclampsia and eclampsia respectively and 74.42% were taking medication. Majority of pre-eclamptics were given Methyldopa i.e. 66.67%, Nifedipine 33.33%, Amlodipine 25.93% whereas in case of eclamptic patients, Magnesium sulphate is the choice of drug in comparison to other anti seizure drug. This study showed that age of the patient, gravidity, parity, long birth interval, altitude are the most significant risk factor for the pre-eclampsia in context of Nepal. This study found that incidence of mild pre-eclampsia is greater than severe pre-eclampsia and eclampsia. It is also concluded that medication i.e. antihypertensive is used in majority of the patient and the most commonly used antihypertensive is Methyldopa and in case of eclamptic patient.

Keywords: Pre-eclampsia, Eclampsia, Incidence, Pregnancy.


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