European Journal of Biomedical and Pharmaceutical Sciences

NOVEL CO-PROCESS EXCIPIENTS USED TO IMPROVE TABLETTING PERFORMANCE.

Mayur A. Deore*, Prashant A. Deore and Pratik S. Chaudhari

ABSTRACT

Tablets are the most preferred dosage form of pharmaceutical professionals because they can be accurately dosed and provide good patient compliance. The ease of manufacturing, convenience in administration, accurate dosing, and stability compared to oral liquids, tamper proof ness compared to capsules, Safe compared to parental dosage forms makes it a popular and versatile dosage form and can be produced at a relatively low cost. Co-processing is a novel process with the interaction of two or more excipients at the sub particle level which in turn provide a synergy of functionality improvements as well as masking the undesirable properties of individual excipients. This main aim of the current review article is to provide a complete overview on recent development in excipient technology and the approaches involved in development of such excipients. The co-processing comprises the most widely explored method for the formulation of directly compressible adjuvants because they are cost effective and can be prepared in-house based on the functionality required. This review highlights the various co processed excipients which will be used to improve the tabletting performance.

Keywords: Excipient, Co-process excipients, Co-Processing.