Abstract
CORRELATION BETWEEN AgNORs AND KI-67 PROLIFERATIVE MARKERS AND THE DEGREE OF DIFFERENTIATION OF BREAST INVASIVE DUCTAL CARCINOMA IN SUDANESE PATIENT

Dalal . Abdelgabar*, Nada Salih Salih and Sara A. Mahmoud Omer

ABSTRACT

Introduction: Cell proliferation reflects the nature of tissue whether it’s malignant or not. In this study we investigated the expression of (Argyrophilic Nuclear Organizing Regions) and Ki-67 proliferative tumor marker (Immunohistochemistry), and their correlation to the grade of differentiation of invasive ductal carcinoma. Objectives: To determines the relationship between AgNORs score and degree of differentiation of invasive ductal carcinoma and the relationship between Ki-67 and grade differentiation of invasive ductal carcinoma. Methodology: Retrospective cross-sectional study done in Khartoum state. Fifty females’ patients diagnosed with invasive ductal carcinoma. Silver stain for detection of expression of AgNORs and Ki-67 proliferative immunological marker were done in histological section of study population. The data were analyzed using SPSS computer program 20.0. Results: Age ranged between 30 and 70 years, varied in tumor grade. Ki-67 showed insignificant expression with tumor grade with maximum of 48% of sample size expression was more than 20% and P.value (P.value=0.234), So as AgNORs expression showed insignificant expression with tumor grade with the maximum of 13% of sample size scored more than 2 dots per cell, and P.value more than 0.005 (P, value=0.737). Conclusions: very strong correlation between Ki-67 reading and AgNORs score with (P.value 0.005

Keywords: .


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW SEPTEMBER ISSUE PUBLISHED

    SEPTEMBER 2020 Issue has been successfully launched on 1 September 2020.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT