European Journal of Biomedical and Pharmaceutical Sciences

NOVEL COUMARINS FROM CEROPEGIA JUNCEA (ROXB.)

Sudha Karayil* Sudheesh P. S. and Vivek C. H.

ABSTRACT

The utility of crude drug was due to its therapeutically active constituents. The phytochemicals with pharmacological activity were extracted from a variety of herbs. Several herbs can help to provide some protection against cancer and many other chronic diseases and it stimulate the immune system. The aim of the present study is to isolate coumrins form the plant Ceropegia juncea (Roxb.). Coumarin derivatives has wide therapeutic properties and is reported by many researchers from different plants belongs to different families. Ceropegia juncea(Roxb.). Also called Soma plant has importance in traditional and Ayurvedic drugs for different ailments. The methanol extract is subjected to isolation and spectral studies. From the spectral data the obtained compounds were reported as Coumarin compounds. Based on the Spectral studies the compound has been elucidated and is reported as novel compounds. 1. (E)-2-cyano-3-(7-hydoxy-4-methyl-2-oxo-2H-chromen-8-yl)-N-(4-methylbenzyl) acryl amide. 2. 4-methyl-8-(2-oxo-2-p-tolyethyl)-2H-Chromen-2-one.

Keywords: Ceropegia juncea (Roxb.).