Rajarshi Sannigrahi*, Debabrata Biswas and Rusa Sannigrahi


Background: Oral submucosal fibrosis(OSF) is a common presentation in ENT OPDs of India with a prevalence of 6.42% due to increased areca-nut and tobacco chewing. Though considered premalignant, biopsy is not routinely indicated for all cases. Objectives: 1. To establish clinico-histopathologic correlation in OSF cases 2. To identify high risk OSF cases needing urgent histopathologic examination. Materials and Methods: A hospital-based cross-sectional observational study was conducted on 100 OSF cases from October’15 to October, 2016. Clinical staging was established based on presence and severity of symptoms, no. of sites involved, size of mouth opening and degree of tongue protrusion. The clinical stage was correlated with histological findings. Results: M:F=5:1. 6 out of 100(6%) of OSF cases turned out to be malignant, of which 5(83.33%) were predicted to be high risk on clinical staging.2 of 8 cases(25%) predicted to be high risk were found to have severe dysplasia. Out of 80 low risk cases, 65(81.2%) had no dysplasia and 15(18.75%) had mild dysplasia. There was significant correlation of clinical staging with histologic findings. Conclusion: The clinical staging method used in this study can categorise OSF cases into high risk, moderate risk and low risk which will decide need for urgent biopsy, close follow up and reassurance respectively.

Keywords: 19Y4NSiG8kkzwWjMD17euEaQ5PErpwxWkP

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