Abstract
CORRELATION OF SIZE OF PRIMARY TUMOUR WITH AXILLARY LYMPH NODE STATUS ON AXILLARY LYMPH NODE DISSECTION IN BREAST CANCER

*Dr Rajat Kumar Jaiswal and Dr. Darshana Tote

ABSTRACT

Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers with an estimated 1.67 million new cancer cases diagnosed in 2012.[1] In less developed regions (883 000 cases) there are slightly more number of cases compared to more developed (794 000) regions.[2] In India, although age adjusted incidence rate of breast cancer is lower (25.8 per 100 000) than United Kingdom (95 per 100 000) but mortality is at par (12.7 vs 17.1 per 100 000) with United Kingdom.[3] AIM - To correlate size of primary tumour with axillary lymph node status on Axillary Lymph Node dissection in breast cancer. Objectives-(i) To correlate the number of positive axillary lymph node with size of primary tumour.(ii)To study the ratio of no. Of lymph node yielded on axillary lymph node dissection to histopathologically positive lymph nodes. Material And Methods: All the patients with primary breast cancer with clinically N0 and N1 nodal status attending in the AVBRH of JNMC will be included in the study. Prospective observation study of 30 cases of female breast cancer. STUDY TYPE – Observational study. SAMPLE SIZE – 30. Results - In present study 30 patients of carcinoma breast, 19 patients were positive for lymph node metastasis. We got that maximum number of patients were present in T3 stage, followed by T2 and T4.Maximum number of lymph nodes were present in T2 followed by T4 and T3.Ratio of total number of identified lymph nodes with lymph nodes positive for metastasis, higher in T4 stage, followed by T2 and T3. Coclusion: 1.Tumour size with grade of tumour must be use to predict the outcome of axillary lymph node metastasis. 2. Ratio of axillary lymph node positivity for metastasis increases with increase in tumour stage.3.While predicting the fate of axilla we need to correlate not only tumour size and grade of tumour but also lymph node invasion, capsular invasion of lymph node and ratio of positive lymph node. Thus we conclude that in low stage tumours complete axillary dissection can be avoided on basis evaluation of these suggested parameters.

Keywords: Carcinoma breast, Tumour size, Axillary lymph node involvement.


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