European Journal of Biomedical and Pharmaceutical Sciences

ASSOCIATION BETWEEN IRON DEFICIENCY AND HELICOBACTER PYLORI INFECTION AMONG SUDANESE PATIENTS IN KHARTOUM STATE – 2018

Duaa M. A. Elkareem, Wafa A. Awad, Belal M. Khalil, Zeinab S. A. Alsayed, Tarig A. M. Hamid*

ABSTRACT

Helicobacter pylori (H. Pylori) are a Gram-negative spirally shaped bacterium. Infection rates are strongly related to poor living conditions; also iron deficiency (ID) is most common nutritional deficiency that associated with poverty. A case-control study was conducted in the Military hospital, Khartoum state, Sudan, where H. pylori infection was diagnosed. Study done during January to April 2018. A total of one hundred and two participants were included, among them 51 with H. pylori infection as a case group, and 51 normal individuals as control group. Venous blood samples were collected from each subject; serum was separated for measurement of iron level. The present study showed that There was a significant decrease of s. iron level among case group with a mean (69.6, 98.1 μg/dL) of case to control group respectively, (P; 0.00). Also show there is no correlation between s. iron level compare with gender, H. pylori infection duration, treatment and other disease with p value (0.11, 0.34, 0.32, 0.58) respectively.

Keywords: Iron deficiency anemia, serum Iron, helicobacter Pylori infection.