European Journal of Biomedical and Pharmaceutical Sciences

CROHN DISEASE OR REGIONAL ILEITIS

Tamilselvi*

ABSTRACT

Crohn disease is a chronic debilitating inflammatory disease of the gastro intestinal tract. It can affect any part of the digestive tract from the mouth to the anus but usually involves the terminal part of the ileum and ileocecal region. Perianal region is commonly affected. The disease like ulcerative colitis is characterized by relapses and remissions. The inflammatory process often starts in the lining mucosa and progresses through the various layers of the intestine (trans mural inflammation) initially. There are small aphthoid ulcers at the sites of intense inflammation and spreads to become but are usually separated by areas of relatively healthy tissue with little or no inflammation (cobble stone appearances).

Keywords: connective tissue, Entro cutaneous fistula, multisystem, inflammation