ANTITYROSINASE ACTIVITY AND ANTIOXIDANT ACTIVITY OF SANTALUM ALBUM & ROSA BRACTEATAE PLANT EXTRACTS FOR SKIN WHITENING ASSAY
Hemalakshmi Mohanarangan* and Dr. D. Chandra Prabha
ABSTRACT
Natural products containing melanin synthesis inhibitory activity are of interest with their potential cosmetic applications and anti-ageing, for example skin-whitening or anti-browning preparations. Various sources of anti-tryosinase compound have been reported but plants source needs to be safe and easily available. The present study attempts to find tyrosinase inhibitors from the selected medicinal plants extracts in three different solvents. The objective of study was to test the effect of herbal formulation on tyrosinase enzyme and to determine the effect so that it can be used as a possible skin lightening agent. The sandalwood and rose petals extract are used for the study to determine its tyrosinsae inhibitory effects at 517nm and 470nm respectively. High invitro quenching effect was observed in ethyl acetate extract along with high tyrosinase inhibition activity, thereby creating a correspondence of anti-oxidant and anti-tyrosinase activity.
Keywords: Anti-tyrosinase, anti-oxidative properties, melanin, skin-lightening assay, skin-whitening assay.
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