Abstract
ANTI HYPERLIPIDEMIC ACTIVITY OF MACROTYLOMA UNIFLORUM LINN

Srinivas Vandavasi* and Grandhi Surendra

ABSTRACT

Hyperlipidemic is the one of the risk factor responsible for atherosclerosis, and cardiovascular diseases.The aim of present work is to screen the antihyperlipidemic activity of Macrotyloma uniflorum Linn leaves extract in cholesterol diet induced hyperlipidemic rats. Wister albino rats were divided into 5 groups and were treated with (control) normal rats without cholesterol diet, (toxic control) cholesterol diet only, (standard)cholesterol diet + Atrovastatin (10mg/kg) b.w , (Test group-1) pet ether extract treated group+ cholesterol diet (Test group-2) chloroform extract +cholesterol diet, (Test group-3) ethanol extract + cholesterol diet . Respectively for 20 days. Data expressed as mean ± S.E.M and analyzed statistically using ANOVA followed by Dunnet’s ‘T’ test and compare with respective control group. Chloroform extract treated group at a dose of 100mg/kg b.w has reduced significantly Total cholesterol, Triglycerides, Low density lipoprotein , Very low density lipoprotein and consecutively increased the level of High density lipoproteins . Ethanolic extract group has shown moderate significant action, whereas petroleum ether extract group has shown very low significant action. It can be conclude that the constituents like alkaloids, flavonoids which are present in chloroform extract of Macrotyloma uniflorum may be responsible for the activity.

Keywords: High density cholesterol level, Low density cholesterol level, Very low density cholesterol level, Macrotyloma uniflorum Linn.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW NOVEMBER ISSUE PUBLISHED

    NOVEMBER 2020 Issue has been successfully launched on 1 November 2020.

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 5.467 to 6.044, due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT