European Journal of Biomedical and Pharmaceutical Sciences

PHYTOCHEMICAL SCREENING, ANALYTICAL PROFILE AND GREEN SYNTHESIS OF SILVER NANOPARTICLES OF SENNA ALEXANDRINA MILL

Zaid Najah*, Mubasher Awad and Madeha Alshawish

ABSTRACT

Phytochemical screening of Senna alexandrina Mill leaves extract exhibited the presence of carbohydrates, saponins, alkaloids, glycosides, proteins, flavonoids, tannins and steroids. The percentage of studied elements (w/w) was as follows; sodium 0.199, potassium 1.076, calcium 1.250 and barium 0.250. Senna alexandrina leaf extract was used as the reducing agent to synthesize silver nanoparticles (Ag-NPs). During synthesis, the color was changed after addition of aqueous extract indicating the formation of silver nanoparticles. UV-Vis spectrophotometer confirmed the formation of Ag-NPs complex by appearance of absorption peak in visible region owing to localized surface Plasmon resonance (LSPR). Quantity of the aqueous extract and heating time of bioreduction reaction effects on the formation of Ag-NPs were evaluated. FTIR analysis showed characteristic common functional groups of hydroxyl, amino, carbonyl, and protein which involved in the synthesis and stabilizing the covering layer of Ag-NPs in aqueous medium.

Keywords: Phytochemical, Senna alexandrina, Green synthesis, FTIR, Sliver nanoparticles.