European Journal of Biomedical and Pharmaceutical Sciences

NOVEL DRUG DELIVERY SYSTEM: A REVIEW

Lalita Chauhan*, Prerna Thakur, Anjali Sharma, Sheetal Sharma and Dr. T. R. Bhardwaj

ABSTRACT

Novel Drug delivery System (NDDS) refers to the approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effects. Other than conventional drug delivery system Novel Drug Delivery System (NDDS) is a system for delivery of drug and a combination of advance techniques. NDDS are far better new dosage forms than conventional dosage forms. In terms of patient compliance, safety and efficacy, evolution of an existing drug molecule from a conventional form to a novel delivery system can significantly improve its performance. Various approaches involves in Novel Drug Delivery System like medical devices or drug-device combination products. The main aim for developing such delivery systems is to minimize drug degradation and loss, to prevent harmful side effects and to increase bioavailability. Based on physical and biochemical mechanisms, Novel drug delivery systems are designed. Physical mechanism or controlled drug delivery system includes dissolution, osmosis, erosion and diffusion. Biochemical mechanism includes gene therapy, liposomes, nanoparticles, monoclonal antibodies. Currently, various drug delivery and drug targeting systems are under development. One of the growing and potential systems for delivery of drugs and enzymes is drug loaded erythrocytes.

Keywords: NDDS, Polymer, Dosage forms, Conventional, Drug release.