European Journal of Biomedical and Pharmaceutical Sciences

INTRAVENOUS DICLOFENAC USED FOR POSTOPERATIVE PAIN PREVENTION IN PATIENT OF THIRD MOLAR EXTRACTION. A RESEARCH ANALYSIS

Dr. Konark and Dr. Anju Singh*

ABSTRACT

Aims and Objective- To assess the analgesic efficacy and tolerance of a single preoperative intravenous infusion of 100 mg of diclofenac in patients undergoing removal of the third molar. Material and method- 100 patients undergoing a standard removal of an impacted lower third molar were given a single dose of 100 mg sodium diclofenac or saline (placebo) intravenously before operation, on a double-blind basis. Pain was measured postoperatively by means of a visual analogue scale hourly for the first 8 h and during the first and second days after operation. Result-Administration of diclofenac resulted in greater pain relief than administration of placebo for the first 3 h after surgery, where after the treatments did not differ. The results suggest that intravenous preoperative diclofenac may be useful in some clinical situations but generally it probably offers little benefit over the corresponding oral treatment.

Keywords: Third molar, pain, placebo, diclofenac.