European Journal of Biomedical and Pharmaceutical Sciences

GREEN SYNTHESIS OF SOME QUINOLINE DERIVATIVES: A REVIEW

Mrunali A. Bhongade* and Dr. Mrs. Manjusha P. Yeole

ABSTRACT

Microwave assisted organic synthesis has emerged as a new ―lead‖ in field of organic synthesis which makes the chemistry to follow approaches of green chemistry. The green chemistry links with safer approaches for process and product development. This technique has provided the excellent momentum for many chemists to switch from conventional methods to microwave assisted chemistry. There has been a dramatic uptake in the use of microwaves as an energy source to promote synthetic transformations. Microwave-assisted synthesis is clearly a method by which the medicinal chemist can achieve goals in a lesser fraction of the time as compared to traditional conductive heating methods. In the present article an attempt was made to focus on basics of microwave assisted synthesis and its improvisations in recent synthetic development of quinolone derivatives. Quinoline is one of the most important N-based heterocyclic aromatic compounds. Quinoline recently is one of the priorities in lead selection by researchers because of its broad range of activities and also for their wide applications.

Keywords: Green Chemistry, Microwave, Quinoline, microwave irradiation, Microwave energy.