A REVIEW UPDATE ON PHARMACOLOGICAL ACTIVITIES AND THERAPEUTIC APPLICATIONS OF NEEM (AZADIRACHTA INDICA) PLANT
Om Prakash Mishra*, Ram Singh, Neelam Verma, Dr. Amresh Gupta, Dr. Amit K. Srivastava
ABSTRACT
Nowadays herbal plants play an important role to maintain the health of populations globally. In Indian traditional system of medicine Ayurveda, above 121 medicinal herbs were discovered which are obtained from the plants used in last century. The medicinal phytoconstituents are isolated from natural medicinal plants resources significantly to improve the process of novel drugs development. Among of all medicinal plants, Azadirachta indica which is commonly known as neem which has been widely used in treatment of various diseases because it has a number of medicinal phytoconstituents. Neem has approximately 140 different types of bioactive chemical constituents in different parts of plant and has attracted worldwide prominence in recent years. Neem has been broadly used in Ayurveda, Unani, Homoeopathic medicine as well as modern medicine (Allopathic medicine). In the different parts of neem tree contains various phytoconstituents which possess anti-diabetic activity, anti-oxidant activity, antibacterial activity, anti-viral activity, anti HIV, anti-inflammatory properties, anti-fungal activity, anthelmintic activity, anti- parasitic activity, anticancer activity, antibone resorption, antispasmodic activity, antipyretic activity, antidiarrheal, immunomodulation properties, hypolipidemic activity, anti-microbial activity, hepatoprotective properties, gastro protective and antifertility properties. The neem plants are used in various fields like medicinal, pharmaceutical, agricultural as well as commercial field by which the living’s life has become easy to live. This review represents a bird's eye view of the various medicinal properties, pharmacological activities and therapeutic uses of neem tree.
Keywords: Phytoconstituents, natural sources, Azadirachta indica, bioactive, Ayurveda, Unani, Homoeopathic, Allopathic.
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