European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON BACTERIAL ISOLATES FROM DACRYOCYSTITIS PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL KOLKATA, WEST BENGAL

Nilay Chatterjee*, Pinaki Biswas, Dr. Kumkum Bhattacharyya, Dr. Saurabh Laskar,
Dr. Anita Nandi (Mitra)

ABSTRACT

Background: Dacryocystitis is one of the most common diseases of eye occurring due to inflammation of the lacrimal sac. It can be of two types: congenital and acquired. Acquired dacryocystitis can be divided into two groups: acute and chronic. Congenital dacryocystitis seen in new born are due to obstruction of the nasolacrimal duct by epithelial debris which produces hindrance in the flow of lacrimal fluid which encourages microbial growth. On the other hand, acute dacryocystitis is more common in women of middle age. Poor hygiene, pond bathing might be the source of infection causing acute infection in nasolacrimal duct resulting in swelling, inflammation, epiphora, and accumulation of pus. Study design: Fifty nine clinically diagnosed patients of dacryocystitis of all age groups and of both sexes were used for the study. Specimens were collected with the help of ophthalmologist. All specimens were subjected to gram staining followed by culture. Antibiotic susceptibility testing was done by Kirby-Bauer disc diffusion method as per CLSI guidelines. Result: Females are more affected than male and highest number of dacryocystitis cases are found among people in the age group of 46 – 60 years. Out of 59 cases of dacryocystitis 9 bacterial isolates were found of which 4 isolates were gram positive and 5 isolates were gram negative organisms. Antibiotic susceptibility tests shows that gram positive isolates were sensitive to vancomycin, oxacillin, linezolid and clindamycin followed by trimethoprim/sulfamethoxazole and gentamicin. Gram negative organisms were mostly sensitive to cefepime followed by amikacin, ceftazidime and piperacilin. Conclusion: The present study revealed that chronic dacryocystitis is the predominant clinical entity found mostly in elderly women. The causative organisms though varied show a predominance of Pseudomonas in our study.

Keywords: Dacryocystitis, Pseudomonas aeruginosa, MSSA.