European Journal of Biomedical and Pharmaceutical Sciences

A RETROSPECTIVE STUDY ON PRESCRIPTION PATTERN OF ANTI-EPILEPTIC DRUGS AMONG PAEDIATRIC PATIENTS AT TERITARY CARE HOSPITAL, MANDYA

Sneha R, Teena Raju, Rishana M and Andrew Gnanaprakasam J*

ABSTRACT

Background: Seizure is a transient occurrence of signs and symptoms resulting from abnormal excessive or synchronous neuronal activity in brain. Children with seizure disorders require prolonged antiepileptic drug (AED) therapy for at least two seizure-free years. Aim: The aim of the study is to review the treatment and management of Anti-epileptic drugs in paediatrics. Objective: To describe the prescribing pattern of AEDs for the paediatrics population in the Department of Paediatric, MIMS, Mandya. Methods and methodology: This was a record based retrospective study on prescribing pattern of Anti-epileptic drugs among paediatrics admitted in the department of paediatrics, MIMS, Mandya. The required data were collected from 177 cases. A well designed data collection form used to collect the required details. The obtained information were documented and subjected to suitable statistical method. Result: Overall 177 case records were analysed. There were a greater number of male children (106) than female (71). The maximum number of patients were found in the age group between 1month and 2yeras (72). Most of the case reported as Simple febrile seizure (168). A total number of 227 drugs were prescribed, the most frequently prescribed class of drugs were Benzodiazepines (124). The majority of drugs were prescribed by oral route as the tablets (126). For the management of seizure, monotherapy had seen in majority of patients (98). Conclusion: The male children were more prone to the seizures than female children. The children between 1 month and below 2years of age were admitted with the complaint of seizures. Simple febrile seizure was the most commonly observed type of seizure. Oral route of administration was mostly prescribed. Hence, this Study concludes that conventional monotherapy was beneficial over combination therapy in paediatric epilepsy.

Keywords: Paediatrics, Epilepsy, Seizure, Prescription pattern, Benzodiazepine.