European Journal of Biomedical and Pharmaceutical Sciences

FORMULATION AND EVALUATION OF ANTIFUNGAL EMULGEL CONTAINING EXTRACTION OF CALOTROPIS GIGANTEA LATEX

*Kalyani M. Dongarwar and Dr. Pravin B. Suruse

ABSTRACT

The present research has been undertaken with the aim to develop antifungal emulgel of calotropis gignatea latex extract. Emulgel comes to favour the hydrophobic drugs to give the advantage of gel. Emulgel have several advantages in the field of dermatology such as being thixotropic, greaseless, easily spreadable, easily removable, emollient non staining, bio friendly, transparent and pleasing appearance The ethanolic extract shows the presence of many biologically active molecules such as flavonoids, steroids, saponins, phenol and glycoside. The latex extract shows significant zone of inhibition and the result are compared with marketed formulation. from this study we conclude that latex extract possesses potent fungicidal activity which may be due to Presence of biologically active ingredient in the ethanolic extract of c. gignatea latex.

Keywords: Calotropis gignatea latex, antifungal activity, zone of inhibition, disc diffusion method.