Abstract
STUDY OF TYPE 2 RESPIRATORY FAILURE IN PATIENTS WITH ACUTE EXACERBATION OF COPD AT A TERTIARY CENTRE

Dr. Pulkit Gupta*, Dr. D. P. Yadav, Dr. G. N. Srivastava, Dr. J. K. Mishra, Dr. N. K. Mishra,
Dr. A. Suresh, Dr. M. Singh

ABSTRACT

Aim: Study of type 2 respiratory failure in patients with acute exacerbation of COPD at a tertiary centre. Methods: This was a single centre case control cross-sectional observational study design including 50 cases and 50 controls. COPD patients more than 40 years of age, having acute exacerbation were included in the study after proper screening. CBC, haemoglobin, LFT, RFT, ABG, hsCRP, spirometry, ECG, ECHO was performed and data was collected and recorded for analysis. Results: Among 50 patients pCO2 as measured by arterial blood gas, 22 patients had pco2 within normal range at the time of presentation of which 21 had a normal pH value and 1 patient had slightly increased pH. 28 patients were hypercapnic and had acidic pH. Conclusion: Type 2 respiratory failure is common is acute exacerbation of COPD. About 56% of patients with acute exacerbation of COPD presented with type 2 respiratory failure.

Keywords: COPD= Chronic obstructive pulmonary disease, CBC= complete blood count, LFT= liver function test, RFT= renal function test, ABG= arterial blood gas analysis, hsCRP= high sensitivity C-reactive protein, ECG= electrocardiogram.


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