Abstract
CYTOTOXIC STUDIES ON SELECTED MEDICINAL PLANTS

P. Elankani*, R. Shakila, R. Ganesan and K. Vinayagamoorthy

ABSTRACT

Methanolic extract of flower bud of Syzygium aromaticum (L.) Merr. & L.M.Perry, leaves of Volkameria inermis L. (syn. Clerodendrum inerme L.) whole plant of Sphaeranthus amaranthoides Burm.f. and combination of these three drugs were studied cytotoxic activity against a human hepato cellular carcinoma cell line, Hep G2 in different concentrations (10, 20, 40 & 80μg/ml) along with standard drug Adriamycin (Doxorubicin)(ADA)(Positive control compound). The results showed that all the extracts were non-cytotoxic at the dose levels studied and all of them showed GI50 only at concentration > 80 μg/ml.

Keywords: Cytotoxic study, Syzygium aromaticum L. Merr. & L.M.Perry, Volkameria inermis L, Sphaeranthus amaranthoides and Adriamycin (ADA).


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