European Journal of Biomedical and Pharmaceutical Sciences

AN OVERVIEW OF RENAL DENERVATION THERAPY IN HYPERTENSION TREATMENT

*Dr. Ajmal Hassin H.

ABSTRACT

Aim: To study and review the positives and negatives of renal denervation therapy. Background: Hypertension is the leading health condition all over the world. According to the World Health Organization, about 1.28 million adults aged 30 to 80 are affected with hypertension worldwide. And in that, less than half of the individuals diagnosed with hypertension are undergoing treatment. In most heart failure patients, hypertension is the most risk factor found, and the patients were taking multiple drug regimens. A specific category of individuals is not so responsive to the medicines so far. In this scenario innovations will help to overcome these conditions, In the modern era of artificial intelligence, it is possible to reduce hypertension with the help of this equipment. This is not an ordinary treatment and does not apply to all hypertensive patients. This type of treatment can be applied to patients with polypharmacy, drug-induced disorders, and patients prone to adverse drug reactions. Numerous studies published in recent years have shown the effectiveness of catheter-based renal denervation treatment in decreasing blood pressure by reducing sympathetic tone. The statement includes; the process of renal denervation therapy, selection of hypertensive patients, mechanism of blood pressure lowering, and expenses. Result: Renal denervation therapy will be very helpful in patients with resistant hypertension and hypertensive urgency as per some studies and in the case of patients with hypertension controlled by monotherapy and dual therapy the procedure is not recommended, but they can also undergo these procedures by their interest. Conclusion: According to the studies renal denervation therapy is helpful in patients with resistant hypertension and there is a significant reduction in the blood pressure. However, the cost of the treatment will not be acceptable to most of the patients in a country like India. If these facilities are available in government hospitals and at an acceptable cost it will be the most helpful way to reduce resistant hypertension, it can reduce drug-induced diseases and the mortality and morbidity with hypertension can be reduced. according to studies the anti-hypertensive property of renal denervation therapy will last up to 48 months. we can conclude this is a solution for hypertension for resistant hypertensive patients, and those who are having hypertensive urgencies, there is no need to do this procedure in patients with normal or hypertension that is controllable by monotherapy and dual therapies.

Keywords: kidney, hypertension, renal denervation, artificial intelligence, innovations, resistant hypertension, Doctor of pharmacy.