Abstract
EVALUATION OF ANTIDEPRESSENT ACTIVITY OF GINKOBILOBA IN RESERPINE INDUCED DEPRESSED ANIMAL MODEL

Dr. J. Raghu Ram*, Dr. Anupama Koneru and Sana Tabassum

ABSTRACT

Depression may disrupt a variety of serotonergic and noradrenergic pathways, leading to a wide range of physiological and psychological distress. Subtypes of the serotonin receptors have been identified, with a focus on 5-HT1 and 5-HT2 in the field of psychiatry. Tolerant skepticism about melancholy places special emphasis on serotonin as a neuro-modulator and a key site of antidepressant efficacy. The kynurenine hypothesis is based on the premise that altered serotonin (5-Hydroxy Trypt.) levels in the brain contribute to the development of depression. Many studies have shown that drugs that inhibit N-Methyl-D-aspartate receptor activity have effects similar to those of active antidepressants.

Keywords: Depression, serotonin and psychological distress.


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