Abstract
COMPUTATIONAL ANALYSIS OF T7SS ASSOCIATED GENES IN MYCOBACTERIUM

Taimoor Khan, Shazia Mannan, Shaeeq Ur Rehman and Shahid Raza*

ABSTRACT

Mycobacteria are a genus of Actinobacteria and belong to the family of Mycobacteriacae. They are immobile, obligate aerobic, acid-fast Gram-positive bacilli with high genomic G+C content (59-66%). Basically, Mycobacteria are a type of germ and exist in many different forms. The most common one causes tuberculosis. Another one causes leprosy. Still others cause infections that are called atypical mycobacterial infections. The study is focused on analysis, identification and annotation of T7SS associated genes and proteins, along with phylogenetic analysis and their comparison at genome level by using bioinformatics tools and software’s. Genome wide annotation will help for studying and analysing future genes at large scale.

Keywords: Actinobacteria, tuberculosis, phylogenetic analysis.


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