European Journal of Biomedical and Pharmaceutical Sciences

INSIGHTS INTO PHYTO PHARMACEUTICAL STUDIES OF BLIND-YOUR-EYEMANGROVE EXCOECARIA AGALLOCHA: A REVIEW

Sravani Mekala*, A. Srivani

ABSTRACT

A large variety of plants with varied medicinal and pharmacological implications are used in the traditional system
of medicine. Excoecaria agallocha L. (Euphorbiaceae), a significant mangrove plant, is reviewed in detail in this
article, along with its ethnobotany, Phytochemistry, and pharmacological effects. It has historically been used to
cure a number of illnesses, including epilepsy, ulcers, leprosy, rheumatism, and paralysis. It is also known as the
blind-your-eye mangrove plant because the latex extracted from the bark has a poisonous nature and has the
potential to temporarily blind people. Many phytoconstituents, primarily diterpenoids, triterpenoids, flavonoids,
sterols, and a few other compounds, have been isolated from the plant. The leaves, stem, latex, and root extracts
incorporated 20 distinct polyphenols, 15 terpenoids, and more than 50 volatile components. The plant also shows a
wide range of pharmacological properties, including antioxidant, antibacterial, anti-inflammatory, analgesic,
antiulcer, anticancer, antireverse transcriptase, antihistamine-release, antifilarial, DNA damage protective,
antidiabetic, and antitumor protecting properties. Therefore, this study might assist researchers who seek to
conduct additional research in these domains.

Keywords: Mangroves; Thillai; Terpenoids; Rutin; Antidiabetic; Diterpenoids; Euphorbiaceae; Excoecaria agallocha; Mangrove; Pharmacology; Phytoconstituents.