Abstract
INVITRO BIOEQUIVALENCE STUDIES OF SIX BRANDS OF ANTI-EPILEPTIC DRUG OF LEVETIRACETAM TABLETS

Dr. Aravanan P.*, Dr. Jeevanandam S., Ragul G., Gopinath B., Naveen N., Haritha C.P. and Nisha Mol M.

ABSTRACT

The purpose of this study was to compare the dissolving profiles of six different pharmaceutical products (Levepil,
Levesam, Epitra, Keppra, Levigress, and Epilive) that are registered and sold commercially in India in order to
assess their characteristics and determine whether they could be used as indicators of in vitro performance. To
carry out the pharmaceutical equivalency medication product's physicochemical property of therapeutic
equivalency with a similar reference listed drug. When a drug product is approved and modifications are made to
its components, composition, or manufacturing process, bioequivalency studies offer information on the product
and its performance. To assess and compare the bioavailability of six distinct levetiracetam brands. Following that,
an assessment was conducted to compare the standard values of six brands of levetiracetam tablets with the Indian
Pharmacopoeia and the United States Pharmacopoeia. Following assessment, the outcome is reported and
compared to the standard values.

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