SEMICARPUS ANACARDIUM LINN AND THEIR ANTICANCER ACTIVITY
Bhagyashri Borde, Suchita Dubey*, Shivam Agarwal, Khushi Tade, Kalyani Lokhande, Samruddhi Aswar, Ankush Bhalerao, Kamlesh Kadam and Geeta Borde
ABSTRACT
Semecarpus anacardium Linn. of the family Anacardiaceae. is a well known medicinal plant in ayurvedic and
siddha medicine. It has been found to have lot of medicinal properties, particularly for its anti-cancerous activity.
semecarpus anacardium, commonly known as the marking nut tree, has been investigated for its potential anticancer
properties. research has shown that the plant exhibitis various pharamacological activities, including antiinflammatory,
anti-arthritic, anti-diabetic, and anti-tumor effects. The active compounds isolated from semecarpus
anacardium, such as bhilawanol, cardol, ant anacardic acids, have demonstracted cytotoxic effects against various
cancer cell lines these compounds have shown potential in inhibiting cancer cell proliferation, including apoptosis,
and preventing angiogenesis. Semecarpus anacardium linn. f. nuts were extracted by using non polar and polar
organic solvents. Hot methanol extract and resinous fraction, isolated from it, showed antitumor activity against
P388 phocyticlym leukaemia in BDF1 mice as judged by their median survival time.
Keywords: Medicinal plant, Anti-cancer, Cytotoxicity, Apoptosis.
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