Abstract
ENCAPCULATION OF GYRINOPS VERSTEEGII WITH IONIC GELATION METHOD

Adi Parwata*, Angga K., Adi Purwa Hita, Alit W., Bawa Putra, Sri Wahyuni and Mega

ABSTRACT

Gyrinops versteegii’s leaves have attracted research interest and have beneficial therapeutic effects through the
antioxidant mechanism because of their high flavonoid content. Photosensitivity and low bioavailability, fast
metabolism are the main limitations for its use, which can be overcome through encapsulation of extracts
(flavonoids) into nanoparticle-based chitosan-tripolyphosphate by ionic gelation method. This study aims to
encapsulate gaharu leaf extract and assess the characterization of the extract nanoparticles formed. Gaharu leaf
nanoparticle extract has a particle size of 312.7 nm with a zeta potential of -16.2 mV and a polydispersity index
value of 0.502, amorphous (non-uniform) morphology, has a tendency to be spherical, and has an imperfectly
spherical shape, has functional groups –OH, -NH, C=O, and a phosphate group. Overall gaharu leaf extract is able
to be encapsulated in chitosan-tripolyphosphate.

Keywords: Gyrinops versteegii, ionic gelation, nanoparticle.


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