European Journal of Biomedical and Pharmaceutical Sciences

PHARMACOGNOSTIC AND PHYTOPHARMACOLOGY STUDY OF ANACYCLUS PYRETHRUM

*Prathmesh Wagh, Radhika Kotame, Abhishek Mokal, Aditya Wagh, Vivek Bhoir and Kiran Dhokale

ABSTRACT

It is a well-known fact that most pharmacological active ingredients come from natural sources; this information predates both high-throughput screening and the post-genomic era. The akarkara roots are widely used in the ancient Eastern herbal medicinal systems of Unani and Ayurveda, which stress holistic health. The botanical name of the medicinal ingredient Akarkara is Anacyclus pyrethrum DC. (family: Compositae). Both traditional and contemporary medical systems assert that the plant Anacycluspyrethrum DC, especially in its roots, has beneficial medicinal properties. Due to its ideal temperament—a mild, somewhat dry warmth—pyrethrum is pure and has a good, robust action. A. Pyrethrum roots have a deep longitudinal fissure, are brown on the exterior, and are compact, stiff, fusiform, and about the size of a little finger. It has few or no hair-like rootlets, and it may still contain leaf remnants at the tip. This analysis focuses on a number of Anacyclus pyrethrum's biological characteristics, such as its acetylcholinesterase inhibition capacity, antimicrobial, antifungal, antidiabetic, antioxidant, anticonvulsant, antidepressant, and anxiolytic effects; it also discusses the herb's anabolic, aphrodisiac, and reproductive qualities as well as its immune-boosting and memory-boosting capabilities. These studies employ a variety of animal models for each activity. The primary finding of this review article is that a variety of solvents, such as ethanol, petroleum, etc., may be utilized to treat a variety of illnesses, including reproductive, anabolic, aphrodisiac, a diabetic, and Alzheimer's disease. The most reliable results are obtained with an ethanolic root extract of Anacyclus pyrethrum.

Keywords: Anacyclus Pyrethrum, Asteraceae, Traditional Uses, Biological Studies, Chemical Composition.