RECENT INNOVATIONS OF NOVEL DRUG DELIVERY SYSTEMS FOR FORMULATION, DEVELOPMENT AND EVALUATION OF ALOE RUBROVIOLACEAE EXTRACT CAPSULES AS NATURACEUTICAL FOR HEPATOPROTECTIVE
Prof. Dr. Mahmoud Mahyoob Alburyhi* and Prof. Dr. Amina El-Shaibany
ABSTRACT
The Aloe Rubroviolaceae is plant widely distributed in Yemen, a large number of medicinal plants have been tested and found to contain active principles with curative properties against a variety of diseases. Liver protective plants contain a variety of chemical constituents like phenols, coumarins, lignans, essential oil, monoterpenes, carotenoids, glycosides, flavonoids, organic acids, lipids, alkaloids and xanthene's. Therefore, a large number of plants and formulations have been claimed to have hepatoprotective activity so the development of plant based hepatoprotective drugs has been given importance in the global market. Aloe Rubroviolaceae is commonly used in traditional medicine for a wide range of ailments including hepatoprotective activity. Aloe Rubroviolaceae was formulated as capsules and evaluated for organoleptic properties and other evaluation parameters. It was concluded that the formulation of Aloe Rubroviolaceae extract medicinal herbs capsules delivery system as an advanced phytotherapy approach for hepatoprotective according to the best results of in-vitro dissolution was found to be 89% within 10 minutes in acid medium and were evaluated.
Keywords: Aloe Rubroviolaceae, Extract, Capsules, Medicinal herbs, Hepatoprotective activity, Phytotherapy.
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