ANTI-INFLAMMATORY ACTIVITY OF SOME MEDICINAL PLANTS FROM KARAWANG, WEST JAVA, INDONESIA – A REVIEW
Aliffia Dwi Rahma, Hanifah Ismayfatin, Wianda Azzahra Audia, Yulianti Khasanah, Ayu Wahyuni, Khesya Shafira Maurizkya, Novi Lavly Fairish, Yasinta Vivia Muthaqimah, Syerli Putri Afriliany,
Lora Irawan, Nisa Dwi Yuliani, Astriani Nurjanah, Neni Nurlela, Anita Fajriyani, Dini Noer Fatwa, and Maulana Yusuf Alkandahri*
ABSTRACT
Numerous nonsteroidal anti-inflammatory drugs reduce pain and inflammation by inhibiting the cyclooxygenase enzyme isoforms' metabolism of arachidonic acid, thereby reducing prostaglandin production. Regrettably, administering nonsteroidal anti-inflammatory drugs often results in a multitude of adverse effects. At present, scholars are commencing the search for novel anti-inflammatory compound candidates derived from naturally occurring substances that have demonstrated anti-inflammatory properties through empirical evidence. Researchers are replacing anti-inflammatory medications, which currently show numerous hazardous adverse effects, with this approach. Scientists have validated a number of medicinal plants indigenous to Karawang, Indonesia, including Apium graveolens, Kaempferia galanga, Andrographis paniculata, Psidium guajava, Moringa oleifera, Aloe vera, and Mangifera indica as possessing anti-inflammatory properties via distinct mechanisms. Therefore, this review article is aimed to discuss the potential of several medicinal plants native to Karawang, Indonesia which have anti-inflammatory effects.
Keywords: Anti-inflammatory, Medicinal plants, Apium graveolens, Kaempferia galanga, Andrographis paniculata, Psidium guajava, Moringa oleifera, Aloe vera, Mangifera indica.
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