Abstract
FORMULATION, DEVELOPMENT AND EVALUATION OF CURCUMA LONGA EXTRACT CAPSULES DELIVERY SYSTEM AS AN ADVANCED PHYTOTHERAPY APPROACH FOR CANCER

Prof. Dr. Mahmoud Mahyoob Alburyhi* and Prof. Dr. Amina El-Shaibany

ABSTRACT

Cancer is a complex disease that is caused by multiple factors and characterized by a rapid and uncontrolled formation of abnormal cells, which may mass together to form a growth or tumor, or proliferate throughout the body, initiating abnormal growth at other sites. Curcuma longa has been used in traditional remedy for a wide range of ailments, including wound healing, urinary and gastrointestinal tract infections, antimalarial, antifungal, anti-inflammatory, antiviral, antibacterial, anaesthetic, chemopreventive, and anticancer, antioxidant, anticoagulant, antifertility, antidiabetic, antiprotozoal, antiviral, antifibrotic, antivenom, antiulcer, Alzheimer's disease, rheumatoid arthritis, hepatoprotective, gastrointestinal tract and cardiovascular system protective effects, and may stimulate immune system, hypocholesterolemic and antihypertensive activities. Curcuma longa was formulated and evaluate as capsules delivery system. It was concluded that the formulation of Curcuma longa extract capsules it was found to be as an optimized capsules according to drug release of Curcuma longa extract capsules delivery system as an advanced phytotherapy approach for cancer.

Keywords: Curcuma longa, Extract, Capsules, Anticancer, Phytotherapy.


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