European Journal of Biomedical and Pharmaceutical Sciences

FORMULATION AND EVALUATION OF ANTIBACTERIAL HERBAL GEL CONTAINING ETHANOL EXTRACT OF LANTANA CAMARA AND NEEM

Swati Agawane*, Mahesh Mali, Mayur Dhaygude, Abhay Kalikate, Vinay Pawar, Vasundhara Patil, Dr. Amit Panaskar, Dr. Bhagyashri Panaskar and Vishal Ghadage

ABSTRACT

Formulation and Evaluation of the herbal gel made from Azadirachta indica and Lantana camera ethanol extract to determine the gel's antibacterial and antimicrobial activities against Staphylococcus aureus bacteria for this, the Agar Cup plate method was used. The diameter of the zones of inhibition (in millimetres) was measured and compared in order to test the antibacterial activity. The area surrounding the well that is clear and contains an antimicrobial agent is known as the zone of inhibition. The antibacterial activity of the herbal gel formulation was assessed against conventional organisms like Staphylococcus aureus and compared to gentamicin (10-mcg). According to the results, there was a good zone of inhibition, but it was smaller than standard. In addition to this, an evaluation of gel formulations was performed considering various parameters, which were pH, appearance, viscosity, spreadability and homogeneity and the result were calculated. The ethanol extract of Lantana camera and Azadirachta indica good antimicrobial and antibacterial properties against the Staphylococcus aureus. It also contains various phytoconstituents, which may be helpful in various health-related Problem.

Keywords: Azadirachta indica, Lantana camera, Herbal gel formulation, Evaluation, antimicrobial, antibacterial activity.