A REVIEW ON SYNTHESIS AND BIOLOGICAL EVALUTION OF BENZIMIDAZOLE DERIVATIVES
Akash Mishra*, Gyan Singh, Anadi Tiwari, Jitendra Malik, Sunil Kumar, Prachi Gupta
ABSTRACT
In the pharmaceutical industry uses benzomidazole, a heterocyclic organic molecule with a significant pharmacophoric group. FTIR spectroscopy was utilized to establish the existence of certain groups. Benzimidazole derivatives, with their multitude of pharmacological actions, are essential in the medical area. include antibacterial, antiviral, anthelmintic, antidiabetic, and anticancer properties. The creation of certain more potent and important compounds was aided by the effectiveness of these therapeutically relevant medications in treating microbial infections and other conditions. Extensive biochemical and pharmacological research has demonstrated the remarkable effectiveness of benzomidazoles against a variety of microorganism strains. The purpose of this paper is to provide an overview of the chemistry of various derivatives of modified benzimidazoles and their pharmacological properties. The benzimidazole nucleus is employed as a preferred structural motif in the creation of a broad spectrum of pharmaceuticals with potential applications in several therapeutic domains.
Keywords: Benzimidazole, anticancer, FTIR spectroscopy, microbial infections.
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