EXTRACTION OF NATURAL SUPERDISINTEGRANTS FROM POTATOS, MAIZE AND TARO (ARABI) FOR FORMULATION OF TABLETS
*Bhagyashri R. Latare, Priti A. Chincholkar A. Akash P. Punwatkar, Aachal P. Kawade and Akansha C. Dahat
ABSTRACT
The aim of the present exploration is to formulate Conventional Ketoprofen tablets. Ketoprofen is a non-steroidal
anti-inflammatory (NSAID) medicine with analgesic, anti-inflammatory, and antipyretic goods. It's extensively
used in the treatment of inflammation and pain associated with rheumatic diseases similar as rheumatoid arthritis,
osteoarthritis, and in soft towel injury. Conventional Ketoprofen tablets were prepared by using wet granulation
system using natural super disintegrants like Potato bounce, sludge bounce and Taro (Arabi) bounce. The set
tablets were characterized for their hardness, frangibility, weight variation, decomposition time and in vitro
dissolution studies. The capability of the tablet to release the medicine briskly depends on the attention and type of
super disintegrants. In this study the conventional tablets containing Potato bounce, sludge bounce and Taro
(Arabi) bounce used as the super disintegrants in the rate of 111. Where the F3 shows better released of medicine.
About 75.81% of the medicine was released from the tablets in 3 hours. Thus, grounded on the evaluation
parameters, in vitro medicine release profile of F3 expression containing Taro (Arabi) bounce is optimized as the
stylish expression with high decomposition rate.
Keywords: Conventional Tablets, Rheumatoid arthritis, Osteoarthritis, Super disintegrants, Ketoprofen, Corn starch, Taro starch, in vitro dissolution test.
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