TO STUDY PRESCRIBING PATTERN AND UTILIZATION OF PROTON PUMP INHIBITORS IN GENERAL PRACTICE
Amish Uprety*, Alisha Sharma Sedai, Dr. Shub Narayan Byar, Dr. Bibek Lamichanne and Dr. Nabin Dhakal
ABSTRACT
Backround: The aim of our study was to assess the prescription pattern in patients prescribed with Proton Pump Inhibitors. Our objectives were to analyze the overall use of Proton Pump Inhibitors with regard to Indication, Dose, dosage and Duration of therapy and also to get a clear understanding of the pattern of PPI prescriptions, assessment of the duration of administration focusing on the various predisposing conditions resulting in their prolonged use. Methodology: A Prospective observational study was conducted in Outpatient Department in Primary hospital. Pertinent information was collected from patients and prescribing pattern of PPIs was analyzed. Results: A total of 182(106 females) patients were enrolled in the study. PPI were prescribed for drug related conditions in 40.65% of patients, 13.18% were prescribed for GI disorders. About 46.17% of the study populations were prescribed with PPI without any indication. The most commonly prescribed PPI was pantoprazole (41.75%) followed by rabeprazole (28.57%) and esomeprazole (8.97%). PPI was co-prescribed for diabetes in 37(20.32%), hypertension 24(13.18%), hyperthyroidism 12 (6.59%) in this study. Conclusion: The results showed that the majority of the PPI prescriptions were made with a high number of doses, without reporting appropriate indications, with some having potential DDIs. The knowledge of prescribing pattern can lead us towards the rational use of drugs and can help us in improving patients’ quality of life as well as economic burden.
Keywords: ppi, prescription pattern, GI disorders, drug utilization.
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