European Journal of Biomedical and Pharmaceutical Sciences

A STUDY ON LIVER ABSCESS - AN ANALYSIS OF ETIOLOGY, PRESANTATION AND MANAGEMENT

Virendra Kumar, *Anuj Sharma, Pradeep Kumar and Sudheer Rathi

ABSTRACT

The objective of this study is to determine the cause, presentation, diagnostic method, management and outcome of liver abscess in patient admitted in our hospital. Liver abscess is common in the tropical region like the Indian subcontinent. The common etiological agents for Liver abscess are E. histolytica (amoebic), bacterial (pyogenic), Mycobacterium tuberculosis, and various fungi. Out of them, Amoebic liver abscess is largely a disease of developing countries like India. Objective: To study the clinical profile, microbiological aetiologies, and management outcomes in patients with liver abscess. Material and methods: A retrospective study was conducted from august 2014 to July 2015, on 44 liver abscess patients at LLRM Medical College, Meerut. History, examination, laboratory and radiological investigation with modalities of management were recorded. Results: Most of the patients in our study were in the age group of 21-40 years. Out 0f 44 patient 34 (77%) were male and 10(23%) were female. Majority of them were from lower socioeconomic class and alcoholic (73% in male). The abscesses were predominantly in right lobe (73%) and solitary (52%). Out of 44 patients, 5 (11%) patients responded to drug therapy alone. Minimally invasive technique (Percutaneous needle aspiration and pigtail drainage) were sucessfull in 38(86%) patients. surgical intervention for rupture in 1(2%) patients. Mortality was 2% only in surgical patient. Conclusions: The commonest presentation was young male, alcoholic of low socioeconomic class having right lobe solitary liver abscess. Appropriate use of minimally invasive drainage techniques reduces mortality.

Keywords: Amoebic liver abscess, Entamoeba Histolytica, Pyogenic abscess of liver, Percutaneous needle aspiration (PNA), Percutaneous catheter drainage.