ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF STERCULIA FOETIDA RIND ALCOHOLIC EXTRACT AGAINST SOME MICROORGANISMS INCLUDING MDR BACTERIA
Ankita Saha, Bhaskar Narayan Chaudhuri, Partha Guchhait and Satadal Das*
ABSTRACT
Antibiotic resistance is one of the global health threats of our time. As microorganisms are developing resistance
to antibiotics, some infectious diseases have become difficult and sometimes impossible to treat. This not only
threatens the lives of those suffering from infection but also undermines the effectiveness of healthcare systems,
worldwide. In this study, the antibacterial activity of the external peel or rind extract in 70% ethanol of Sterculia
foetida, commonly known as Java olive, was investigated against Staphylococcus aureus, Escherichia coli,
Candida albicans, multidrug-resistant (MDR) E. coli, and MDR Klebsiella spp. by broth microdilution method
for determining MIC levels. The minimal inhibitory concentration (MIC) of the extract was tested against various
types of bacteria and fungi, including MDR E. coli, and MDR Klebsiella spp. The results showed that the extract
was effective against all strains tested, except MDR E. coli. These data suggest that Sterculia foetida can be an
effective and alternative candidate for developing antimicrobial compounds.
Keywords: Sterculia foetida, MDR bacteria, MIC level.
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