IN-VITRO ASSESSMENT OF ANTIMICROBIAL ACTIVITY OF INDIAN HERBS AND CITRUS FRUIT JUICES AGAINST ENTEROPATHOGENIC BACTERIA
Preeti G. Dharmik*, Ashok V. Gomashe and Suhas S. Deotalu
ABSTRACT
The worldwide increase of multidrug resistance in both community- and health-care associated bacterial infections has impaired the current antimicrobial therapy, warranting the search for other alternatives. We aimed to find the in vitro assessment of antibacterial activity of Indian herbal plant extracts viz., Aloe vera, Neem, Bryophyllum, Lemongrass, Tulsi, Oregano, Rosemary and Thyme and four citrus fruit juices viz. Amla, Carrot, Beet and Lemon against a series of MDR bacteria of clinical relevance viz Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Vibrio cholerae and Salmonella typhi. Results showed the inefficiency of all the tested antibiotics against the given test organisms and isolates showed high degree of resistance (70%-100%) against the therapeutic agents. The MDR isolates were treated with extracts and juices. The inhibition was observed with the individual extracts and citrus fruit juices. Plant extracts have great potential as antimicrobial compounds against microorganisms. Thus, they can be used in the treatment of infectious diseases caused by resistant microbes.
Keywords: Enteropathogenic bacteria, Indian herbs, Citrus fruits.
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