European Journal of Biomedical and Pharmaceutical Sciences

A COMPARATIVE ASSESSMENT OF THE BACTERIAL PROFILE AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN IN CLINICALLY DIAGNOSED URINARY TRACT INFECTION (UTI) IN PREGNANT AND NON-PREGNANT WOMEN IN A TERTIARY CARE HOSPITAL OF PUNJAB

Nancy Bandral*, Dr. Arindam Adhikary, Saryu Sharma and Dr. Pankaj Kaul

ABSTRACT

Objectives: Urinary tract infection (UTI) is defined as the presence of microbial pathogens in the urinary tract and
women of the reproductive age group (20-45 years) are the most vulnerable population. In the present study, an
attempt has been made to compare the bacterial profile of the patients with clinically diagnosed UTI in pregnant
and non- pregnant women, also to assess the antibiotic susceptibility pattern of uropathogens. Methods: A total of
500 pregnant and non-pregnant women of Mohali district were considered as sample for the present study. Several
local hospitals and laboratories were considered and necessary consent was obtained from authorities along with
the patients. Urine samples were collected with UTI symptoms and cultured. Antibiotic susceptibility test was
performed following standard procedure. Results: The analysis of urine cultures identified Escherichia coli
(E.coli) as the predominant pathogen in 85% of the cases. Other notable pathogens included Klebsiella
pneumoniae (7%), Proteus mirabilis (5%) and staphylococcus (3%). Conclusion: It might be concluded that gram
negative organisms were responsible for more cases of UTI and E. coli was the main causative agent. E. coli was
sensitive to commonly prescribed drugs, like ciprofloxacin, amikacin and imipenem.

Keywords: Bacterial profile, Antibiotic susceptibility pattern, Urinary tract infection, Pregnant and nonpregnant women of Mohali.