European Journal of Biomedical and Pharmaceutical Sciences

A CONCISED REVIEW ON DIFFERENT ANALYTICAL TECHNIQUES USED ON LOSARTAN POTASSIUM

Kunj Patel*, Krishna Kalsara, Dr. Umesh Upadhaya and Dr. Chainesh Shah (PG Coordinator)

ABSTRACT

The FDA authorized losartan, the first AT1 receptor blocker (ARB), was approved fifteen years ago. Over those
years, physicians and researchers have amassed a significant body of evidence regarding the advantages of
losartan, especially with regard to hypertension and kidney disease. These advantages include lowering the risk of
stroke in individuals with left ventricular hypertrophy, reducing proteinuria, and delaying the development of
diabetic nephropathy. In this review article various analytical techniques are mentioned for estimation of losartan
individually and in combination with other drugs. There are number of articles available but to gather all the
information in this article is not possible but in contrast this article provides information available on analytical
methods on this drug for future research.

Keywords: losartan, UV spectroscopy, HPLC, RP-HPLC, HPTLC, hypertension.